I am an interventional radiologist, founder and Chief Director of the Okuno Clinic in Tokyo, Japan. After my training in radiology, I was engaged in basic and clinical research for several years. My initial research focus at
the Keio University/Tokyo was vascular biology and basic research in pathological angiogenesis.

. From early
on in my career as an interventional radiologist, I had a strong interest in the question of whether embolization can provide a new approach to effectively reduce chronic inflammation and alleviate pain. I later successfully introduced transarterial embolization for the treatment of chronic musculoskeletal disorders, such as knee osteoarthritis (OA) 2 and frozen shoulder3, and reported its safety and usefulness in the world for the first time by conducting clinical researches. I have authored and co-authored 20 peer-reviewed publications related to embolization for musculoskeletal disorders, in particular knee OA with superselective GAE. I reported the safety and efficacy of this innovative technique resulting in significant and sustained pain relief in clinical studies, which have since been confirmed by other researchers
1. Okuno, Y., Nakamura-shizu, A., Otsu, K., Suda, T. & Kubota, Y. Pathological neoangiogenesisdepends on oxidative stress regulation by ATM. Nature Med 2012
2. Okuno Y, Korchi AM, Shinjo T, Kato S. Transcatheter arterial embolization as a treatment for medial knee pain in patients with mild to moderate osteoarthritis. Cardiovasc Intervent Radiol. 2014 Jul 4.
3. Okuno Y, Oguro S, Iwamoto W, Miyamoto T, Ikegami H, Matsumura N. Short-term results of transcatheter arterial embolization for abnormal neovessels in patients with adhesive capsulitis: a pilot study. J Shoulder Elbow Surg.